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By promoting vasodilation and reducing fluid volume through natriuresis, semaglutide helps regulate blood pressure, making it a potentially valuable treatment option for individuals with hypertension

Interestingly, these authors also found that iNKTs activation is required for maximal weight loss effect in liraglutide therapy that also concurred with an increase in Fgf21 expression in eWAT

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Some also report worsening acid reflux or new symptoms of gastroesophageal reflux disease (GERD)